Trimethylamine N oxide (TMAO) is a small molecule produced in humans primarily by the gut liver axis and has become an important biomarker, and possible mediator, of cardiometabolic and renal disease. Dietary choline, phosphatidylcholine ( Trimethylamine NOxide Generated by the Gut Microbiota Is Associated with Vascular Inflammation: New Insights into Atherosclerosis Liu 2020 Mediators of Inflammation Wiley Online Library Characterization of TMAO productivity from carnitine challenge facilitates personalized nutrition and microbiome signatures discovery Microbiome Springer Nature Link L Carnitine intake and high trimethylamine N oxide plasma levels correlate with low aortic lesions in ApoE transgenic mice expressing CETP Atherosclerosis Frontiers The gut microbial metabolite trimethylamine N oxide and cardiovascular diseases This molecule links your diet to stroke and Alzheimer'shere's how to stop it