Smoking and vaping don't affect your eligibility to donate. Become a donor and give life today. Can you donate blood if you smoke? Can You Donate Plasma If You Smoke Weed? https: www.greenreliefhealth.com Can You Donate Blood If You Smoke? Cannabis, Nicotine, and More We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Can Vaping Cause Lung Cancer? Here's What We Know.